Selected Research Findings
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Lifetime Estradiol Exposure and Risk of Depression during the Menopausal Transition: The Study of Women's Health Across the Nation
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Citation: Marsh W, Bromberger J, Crawford S, Randolph J, Kravitz H, Joffe H, Leung K, and Soares C: Lifetime Estradiol Exposure and Risk of Depression during the Menopausal Transition: The Study of Women's Health Across the Nation. North American Menopause Society 22nd Annual Meeting poster #1165714, Washington DC, Sept 21st-24th 2011.
Wendy Marsh MD MS, a SWAN investigator from the University of Massachusetts, and her co-authors were awarded a top 2011 Poster Prize at the 22nd Annual North American Menopause Society (NAMS) Meeting in Washington DC on September 24th. Using the SWAN database, Dr. Marsh and colleagues' study found that a longer duration of estradiol exposure, measured by years from menarche to menopause, prior to entering the menopausal transition was protective against depression during the menopausal transition.
Founded in 1989, The North American Menopause Society (NAMS) is North America's leading nonprofit organization dedicated to promoting the health and quality of life of all women during midlife and beyond through an understanding of menopause and healthy aging. It has a multidisciplinary membership of 2,000 leaders in the field - including clinical and basic science experts from medicine, nursing, sociology, psychology, nutrition, anthropology, epidemiology, pharmacy, and education. The annual meeting provides a dynamic forum in which clinicians and researchers interested in menopause meet and exchange ideas.
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Major Depression During and After the Menopausal Transition: Study of Women's Health Across the Nation (SWAN)
- Joyce Bromberger, PhD, co Principal Investigator of the SWAN Pittsburgh site and Principal Investigator of the SWAN Mental Health study, published a paper titled "Major Depression During and After the Menopausal Transition: Study of Women's Health Across the Nation (SWAN)" in Psychological Medicine 2011;41(9):1879-1888. The results have been reported by Psychiatric News and Harvard Women's Health Watch.
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Samar El Khoudary, PhD, a SWAN investigator receives the first place in clinical and translation research poster session at the 19th Annual Congress on Women’s Health, Arlington, VA, 1-3 April 2011
- As a result for her participation in the 19th Annual Congress on Women’s Health, Arlington, VA, 1-3 April 2011, Samar El Khoudary, PhD, a SWAN investigator from the Coordinating Center at the University of Pittsburgh has been awarded the NIH Office of Research on Women's Health, Women's Health and Sex Differences Research Poster Session First Place/Clinical and Translational Research. Dr. El Khoudary research work concluded that during the menopausal transition, mainly at the late peri-menopause stage, the carotid artery undergoes an adaptation that is reflected in changes in wall thickness and diameter. These changes may impact the vulnerability of the vessel in the postmenopausal period.
The Women's Health Congress is one of the most exciting and innovative update on the whole gamut of women's health issues. It is presented by Journal of Women's Health
and VCU Institute for Women's Health In collaboration with National Cancer Institute and NIH Office of Research on Women's Health. Over 950 physicians, scientists, health care professionals and medical students have attended this meeting.
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Endogenous Sex Hormones Impact the Progression of Subclinical Atherosclerosis in Women during the Menopausal Transition
- Samar El Khoudary, PhD, a SWAN investigator from the Coordinating Center at the University of Pittsburgh, has been chosen as one of the recipients of the Trudy Bush Fellowship for Cardiovascular Research in Women’s Health, for her work titled “Endogenous Sex Hormones Impact the Progression of Subclinical Atherosclerosis in Women during the Menopausal Transition.” Dr. El Khoudary’s scientific findings will be presented during the Joint Conference: Nutrition, Physical Activity and Metabolism and Cardiovascular Disease Epidemiology and Prevention 2011 Scientific Sessions, scheduled for March 22-25 in Atlanta, Georgia. This award is named for Dr Trudy Bush to honor her outstanding leadership in the field of women’s health and contributions to cardiovascular science. .
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An Actigraphy Study of Sleep and Pain During the Menopausal Transition: The SWAN Sleep Study
- Howard Kravitz, DO, MPH, Principal Investigator of the Chicago SWAN site, presented his findings titled "An Actigraphy Study of Sleep and Pain During the Menopausal Transition: The SWAN Sleep Study. " at the North American Menopause Society (NAMS) meeting on October 8, 2010 in Chicago, Illinois. The results have been reported by The Brilliant Stories and WebMD.
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Highlights from SWAN: Focus on Menopause
- Study of Women’s Health Across the Nation (SWAN), an ongoing cohort study evaluating longitudinal changes in biological, behavioral, and psychosocial parameters in women as they transition from pre- to postmenopause is of high relevance to understanding healthy aging in midlife women and beyond. Funded initially in September 1994, SWAN is a cooperative agreement consisting of seven clinical field sites, a central reproductive hormone laboratory, a coordinating center (CC), an advisory panel and a repository of blood, urine and DNA specimens. A set of amended competing renewal applications to continue SWAN for a fourth five-year funding cycle (SWAN IV), was submitted in July 2008 and the core study was refunded in the spring of 2009. The study is supported by NIA-DGCG, the National Institute of Nursing Research (NINR) and the NIH Office of Research on Women’s Health (ORWH). Ancillary studies are supported by the NNA/NIA, NIMH, NHLBI, and the National Center for Complementary and Alternative Medicine (NCCAM).
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Obesity Impacts the Role of Endogenous Reproductive Hormones in Coronary and Aortic Calcification Among Women at Midlife
- Samar El Khoudary, PhD, a SWAN investigator from the Coordinating Center at the University of Pittsburgh, presented her findings titled "Obesity Impacts the Role of Endogenous Reproductive Hormones in Coronary and Aortic Calcification Among Women at Midlife" at the American Heart Association's Specialty Conferences in 2010 and is among the top 10 percent of accepted abstracts. To honor Samar El Khoudary's top-scoring abstract, the findings have been selected to be re-presented as a poster presentation at the Scientific Sessions 2010, November 13-17, in Chicago. As the premiere cardiovascular conference in the world, with over 20,000 professional attendees, presenting at Scientific Sessions will provide greater visibility and a broader reach for the science.
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Lactation and Subsequent Maternal Visceral Adiposity
- Candace McClure, PhD, a SWAN investigator from the Coordinating Center at the University of Pittsburgh, presented her findings titled "Lactation and Subsequent Maternal Visceral Adiposity" at the American Heart Association, 50th Annual Conference on Cardiovascular Disease Epidemiology and Prevention, San Francisco, CA, March 2-5, 2010. The results have been reported by Businessweek and Kompas (an Indonesian news site).
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Are Changes in Cardiovascular Disease Risk Factors in Midlife Women Due to Chronological
Aging or to the Menopausal Transition?
- Karen Matthews, PhD, Principal Investigator of the Pittsburgh SWAN site, published a paper titled "Are Changes in Cardiovascular Disease Risk Factors in Midlife Women Due to Chronological Aging or to the Menopausal Transition?" in the Journal of the American College of Cardiology. 2009;54:2366-2673. Co author Kim Sutton-Tyrrell, DrPH, Principal Investigator of the SWAN Coordinating Center at the University of Pittsburgh, presented the results at the JACC Press Conference and on Pittsburgh news channels KDKA and WTAE. The study results have been reported by the Wall Street Journal, CNN, MSN, US News & World Report, Cardiology Today, Health News, Endocrine Today, American Medical News, MedPage Today, WIBW, Philly53, KDKA, KFSM, Examiner, Leeftijdloze Schoonheid (a Netherlands magazine), and Harvard Health Watch.
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Accelerated hip bone loss in diabetic women across menopause
- Naila Khalil, PhD, a SWAN investigator from Wright State University, received a young investigator award from The American Society for Bone and Mineral Research (ASBMR) for her presentation titled "Bone changes and incident fractures during menopause in women with diabetes in SWAN."
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Hot flashes and carotid intima media thickening: Findings from the SWAN Heart Study
- Rebecca Thurston, PhD, a SWAN investigator from the University of Pittsburgh, received two awards from the North American Menopause Society (NAMS). Rebecca's work on hot flashes was received the NAMS/Duramed Pharmaceuticals, Inc. Vasomotor Research Award and the NAMS New Investigator Award.
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Hopelessness, Depressive Symptoms and Carotid Atherosclerosis in Women: The Study of Women's Health Across the Nation (SWAN) Heart Study
- Susan Everson-Rose, PhD of the University of Minnesota and a SWAN investigator published a paper titled "Hopelessness, Depressive Symptoms and Carotid Atherosclerosis in Women: The Study of Women's Health Across the Nation (SWAN) Heart Study" in Stroke 2009;40(10):3166-3172. Her findings have reported in a number of media sources including US News & World Report, ABC News, MSNBC, WCCO, China Daily, The Times of India, Science Daily, Herald Sun, Science Blog and One India.
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Effects of the menopause transition and hormone use on cognitive performance in midlife women
- Gail Greendale, MD and Principal Investigator of the UCLA SWAN site published a paper titled "Effects of the menopause transition and hormone use on cognitive performance in midlife women" in Neurology 2009;72(21):1850-1857. The article has been covered by a number of lay media sources including the New York Times, AARP and ABC News.
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Testosterone and Visceral Fat in Midlife Women: The Study of Women's Health Across the Nation (SWAN) Fat Patterning Study
- Imke Janssen, PhD and investigator at the Chicago SWAN site published a paper titled "Testosterone and Visceral Fat in Midlife Women: The Study of Women's Health Across the Nation (SWAN) Fat Patterning Study" in Obesity doi 10.1038/oby.2009.251. The article has been covered by lay media sources including Science Daily, Examiner, EmaxHealth and Medical News Today.
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Marital Happiness and Sleep Disturbances in a Multi-Ethnic Sample of Middle-Aged Women
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Menopause and the Metabolic Syndrome: The Study of Women's Health Across the Nation (SWAN).
- Imke Janssen, PhD, and investigator at the Chicago SWAN site published a paper titled "Menopause and the Metabolic Syndrome: The Study of Women's Health Across the Nation (SWAN)" in Archives of Internal Medicine 2008;168(14):1568-1575. The article has been covered by lay media sources including Reuters.
- Parade article: Embrace The Change
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Sexual Functioning and Practices in a Multi-Ethnic Study of Midlife Women: Baseline Results from SWAN
- The article "Sexual Functioning and Practices in a Multi-Ethnic Study of Midlife Women: Baseline Results from SWAN" by Virginia S. Cain published in the Journal of Sex and Research 2003 Aug;40(3):266-76 has been selected by SSSS (Society for the Scientific Study of Sexuality)for the Henry Beigel Research Award, which honors the best paper published in the Journal of Sex Research in the past year.
- Finding from published manuscripts
- Highlights from SWAN Study
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